Vocal aging and the impact on daily life: a longitudinal study

Longitudinal studies on vocal aging are scarce, and information on the impact of age-related voice changes on daily life is lacking. This longitudinal study reports on age-related voice changes and the impact on daily life over a time period of 5 years on 11 healthy male speakers, age ranging from 50 to 81 years. All males completed a questionnaire on vocal performance in daily life, and perceptual and acoustical analyses of vocal quality and analyses of maximum performance tasks of vocal function (voice range profile) were performed. Results showed a significant deterioration of the acoustic voice signal as well as increased ratings on vocal roughness judged by experts after the time period of 5 years. An increase of self-reported voice instability and the tendency to avoid social parties supported these findings. Smoking males had a lower speaking fundamental frequency compared with nonsmoking males, and this seemed reversible for males who stop smoking. This study suggests a normal gradual vocal aging process with clear consequences in daily life, which should be taken into consideration in clinical practice as well as in studies concerning communication in social life.     

Nuclear Halo-Like Phenomena of 6,8He and Nuclear Short Range Correlation

Based on the nuclear short range correlation in a halo-like nucleus, theoretical analysis of the experimental cross sections for small-angle elastic p-4,6,8He scattering at the energy of about 0.7 GeV has been performed in the framework of Glauber multiple scattering theory. Our theoretical calculations reproduce the corresponding experimental data quite successfully. These good agreements confirm that the nuclear halo-like phenomena may originate from the short range correlation between nucleons in a halo-like nucleus.     

激光荧光肺癌诊断图象处理系统滤光片的研制

本文论述用于激光荧光肺癌诊断图象处理系统滤光片的膜系设计,制备这套滤光片所采取的工艺措施,最后给出研制的结果。     

Synthesis of tin oxides SnO2–x in the entire composition range (x = 0 to 1) by ion‐beam sputter‐deposition

Ion‐beam sputter‐deposition (IBSD) was used to reactively deposit tin oxide crystalline films at oxygen fluxes of 3–15 sccm and at substrate temperatures of 100–600 °C. Analysing the samples by X‐ray diffraction and Raman spectro‐ scopy yields a map of the crystalline structures in dependence on the growth parameters. In addition to SnO₂, pure SnO films of high quality and an intermediate phase such as Sn₂O₃ or Sn₃O₄ can be reproducibly obtained. Thus, IBSD is, to our knowledge, the only thin‐film deposition technique verified yet to reliably produce samples in the entire composition range of tin oxides. (© 2015 WILEY‐VCH Verlag GmbH &Co. KGaA, Weinheim)     

激光距离选通成像门宽对图像信噪比影响

为了解不同激光测距精度下的选通成像信噪比,本文利用外场实验系统对不同门宽条件下的图像信噪比进行了分析。首先,根据激光距离选通成像理论建立作用距离模型,初步确定系统各项参数。在此基础上,构建外场实验系统,并利用实验系统进行外场实验研究。对不同门宽条件下的图像进行分析对比,获得门宽与图像信噪比关系曲线。实验结果表明:在门宽2 μs范围内,图像信噪比≥8,图像质量满足自动识别要求,充分证明了距离选通成像系统对测距精度要求较低,完全满足实际应用需求。     

Electronic spectra and intersystem spin‐orbit coupling in 1,2‐ and 1,3‐squaraines

The main photophysical properties of a series of recently synthetized 1,2‐ and 1,3‐squaraines, including absorption electronic spectra, singlet‐triplet energy gaps, and spin‐orbit matrix elements, have been investigated by means of density functional theory (DFT) and time‐dependent DFT approaches. A benchmark of three exchange‐correlation functionals has been performed in six different solvent environments. The investigated 1,2 squaraines have been found to possess two excited triplet states (T₁ and T₂) that lie below the energy of the excited singlet one (S₁). The radiationless intersystem spin crossing efficiency is thus enhanced in both the studied systems and both the transitions could contribute to the excited singlet oxygen production. Moreover, they have a singlet‐triplet energy gap higher than that required to generate the cytotoxic singlet oxygen species. According to our data, these compounds could be used in photodynamic therapy applications that do not require high tissue penetration. © 2014 Wiley Periodicals, Inc.     

A rapid method for simultaneous determination of 52 marker compounds in Xiao‐Qing‐Long‐Tang by ultra high performance liquid chromatography coupled with quadrupole time‐of‐flight mass spectrometry†

Xiao‐Qing‐Long‐Tang (XQLT) is a classical Chinese medicine formula. It is generally used for the treatment of common cold, bronchial asthma, and allergic rhinitis in Asia. In this study, a multicomponent quantification fingerprinting approach based on ultra high performance liquid chromatography coupled with quadrupole time‐of‐flight mass spectrometry has been developed for the analysis of compounds in XQLT in 14.5 min. A total of 52 compounds were identified by co‐chromatography of sample extract with authentic standards and comparing the retention time, UV spectra, molecular ions and characteristic fragment ions with those of authentic standards, or tentatively identified by MS^E determination along with Mass Fragment software. Moreover, the method was validated for the simultaneous quantification of 16 components in XQLT commercial products. The method is practical for comprehensive standardization of XQLT and holistic comparison of its commercial products from different manufacturers.     

Sensitivity of the Hermite rank

The Hermite rank appears in limit theorems involving long memory. We show that a Hermite rank higher than one is unstable when the data is slightly perturbed by transformations such as shift and scaling. We carry out a “near higher order rank analysis” to illustrate how the limit theorems are affected by a shift perturbation that is decreasing in size. We also consider the case where the deterministic shift is replaced by centering with respect to the sample mean. The paper is a companion of Bai and Taqqu (2017) which discusses the instability of the Hermite rank in the statistical context.     

Range sets for weak efficiency in multiobjective linear programming and a parametric polytopes intersection problem

ABSTRACT

The aim of this paper is to obtain the range set for a given multiobjective linear programming problem and a weakly efficient solution. The range set is the set of all values of a parameter such that a given weakly efficient solution remains efficient when the objective coefficients vary in a given direction. The problem was originally formulated by Benson in 1985 and left to be solved. We formulate an algorithm for determining the range set, based on some hard optimization problems. Due to toughness of these optimization problems, we propose also lower and upper bound approximation techniques. In the second part, we focus on topological properties of the range set. In particular, we prove that a range set is formed by a finite union of intervals and we propose upper bounds on the number of intervals. Our approach to tackle the range set problem is via the intersection problem of parametric polytopes. Thus, our results have much wider area of applicability since the intersection (and separability) problem of convex polyhedra is important in many fields of optimization.     

Monotonicity and phase diagram for multirange percolation on oriented trees

We consider Bernoulli bond percolation on oriented regular trees, where besides the usual short bonds, all bonds of a certain length are added. Independently, short bonds are open with probability p and long bonds are open with probability q. We study properties of the critical curve which delimits the set of pairs (p,q) for which there are almost surely no infinite paths. We also show that this curve decreases with respect to the length of the long bonds.